From Marvel Comics, first appeared in the Secret Wars series where Spider-Man gets his black costume that becomes Venom. Titania was just some random girl from Detroit that Dr. Doom gave powers to, and all of a sudden she could beat up She-Hulk and Rogue without breaking a sweat.
Created in Clip Studio Paint Pro on a Surface Pro 4. Here is the time lapse video:
And here is the Black & White line art version: